The global economy is in an extraordinary state of flux. Trade policy is unsettled. Recently enacted tax legislation provides fiscal stimulus while adding to the long-term national debt. Brexit remains to be negotiated, and China and India’s influence on the global economy continues to grow. Monetary policy continues to be an issue and concern prevails that the Trump Administration will politicize the Federal Reserve. These macroeconomic trends have significant implications for corporate strategy across a wide range of industries. This panel reviews the state of the global economy and connects macroeconomic trends to practical, bottom-line issues that arise in corporate boardrooms.